What is Pristiq®?

Pristiq® (desvenlafaxine) belongs to the new generation class of serotonin-norepinephrine reuptake inhibitors (SNRIs).1,2 Pristiq® works by regulating the levels of serotonin and norepinephrine in the brain, thereby improving symptoms of emotional distress.3

Relieve emotional distress
Regain the life you deserve3

product

iconThe benefits of Pristiq®

1
advantage 1

Significantly improves depressive symptoms as early as Week 14

Study showed that compared with placebo, treatment with Pristiq® resulted in significant improvements in depressive symptoms as early as Week 1.

2
advantage 2

Significantly improves functional impairment5

Study showed that compared with placebo, Pristiq® offers significant improvement in patients’ social, family, and work-life functioning within eight weeks.

3
advantage 3

High chance of remission6,7

Remission rate of emotional distress after receiving Pristiq® is higher than placebo. Serotonin–norepinephrine reuptake inhibitor (SNRIs), including Pristiq® is found to provide better remission rate than selective serotonin reuptake inhibitor (SSRIs).

4
advantage 4

Less likely to cause side effects8

A large comprehensive study including nine clinical trials showed that after taking Pristiq®, the discontinuation rate due to side effect is similar to placebo.

PristiqHow do I take Pristiq®?9

  1. Pristiq® is an oral drug, can be taken with or without food
  2. The recommended dose for Pristiq® is 50mg once daily
  3. Tablets must be swallowed whole with fluid and not divided, crushed, chewed and dissolved
  4. Avoid alcohol consumption while taking Pristiq®
section-2

PristiqThe safety of Pristiq®

The most common side effects with Pristiq® include nausea, dizziness, insomnia, constipation, fatigue, anxiety, and decreased appetite.7 Side effects, if they occur, usually emerge in the first week after taking Pristiq®, and are mostly mild in severity, transient in nature, and often subside.7,10 Studies with Pristiq® 50mg have shown that the rate of discontinuation due to side effects was 4.1%, similar to placebo, at 3.9%.8

section-2
assessmentPHQ-9PHQ-9

Mental Health Assessment

Know More About
My Mental Health

References

  • 1. Stahl's Essential Psychopharmacology: Neuroscientific Basis and Practical Applications, 4th edition, Cambridge University Press, 2013.
  • 2. Kennedy SH, et al. Can J Psychiatry. 2016;61(9):540–560.
  • 3. Thase ME, et al. CNS Spectr. 2009;14(3):144–154.
  • 4. Katzman MA, et al. J Clin Psychopharmacol. 2017;37:555–561.
  • 5. Soares CN, et al. CNS Spectr. 2019;24(3):322–332. 
  • 6. Machodo M, et al. J Clin Pharm Ther. 2010;35:177–188.
  • 7. Boyer P, et al. Int Clin Psychopharmacol. 2008;23:243–253.
  • 8. Clayton AH, et al. CNS Spectr. 2009;14(4):183–195.
  • 9. Pristiq® (desvenlafaxine) Prescribing Information. Pfizer Corporation Hong Kong Limited: Version March 2022.
  • 10. Liebowitz MR & Tourian KA. Prim Care Companion J Clin Psychiatry. 2010;12(3):PCC.09r00845. 

 

PP-PRQ-HKG-0385 JUN 2023